Semaglutide is a modified molecule our bodies make, called a GLP-1 analog. It works by increasing insulin production and lowers glucagon secretion as well as targets areas in the brain that regulate appetite and food intake. A small change in the molecule allows the drug to last weeks in our bodies rather than the natural version our bodies make, which lasts minutes. Originally used for diabetes and sold under the name Ozempic®. In June 2021, Wegovy, brand name Semaglutide, was FDA approved for weight loss.
If you or any family members have been diagnosed with Multiple Endocrine Neoplasia Syndrome Type 2 or Medullary thyroid cancer you should not take Semaglutide. If you have ever had pancreatitis consult with your medical provider as using Semaglutide can increase the risk of developing pancreatitis.